In total, 450 cases of hepatitis associated with HSW were reported. Lei X, Chen J, Ren J, et al. The two forms have different properties: the raw HSW is used for detoxification, eliminating carbuncle, preventing malaria, and relaxing bowel, whereas the processed HSW is used for nourishing liver and kidney, supplementing essence and blood, blackening hair, strengthening bones and muscles, eliminating dampness, and reducing lipid [2]. As a Chinese herb, it was recorded most early in “Kaibao Bencao” published by the imperial court of the Song Dynasty (973-974 A.D.) [1]. Of the 450 patients, two cases who received liver transplantation and seven who died, the remaining 441 cases recovered or had liver function improvement after discontinuing HSW products and conservative care. COVID-19 is an emerging, rapidly evolving situation. An extensive search of 6 medical databases was performed up to June 2014. Evid Based Complement Alternat Med. Please enable it to take advantage of the complete set of features! Based on the above information we know that HSW associated with liver injury can occur at any age group and with no gender orientation. Evidence of its potential side effect on liver injury has accumulated and received much attention. Blood lipid-regulation of stilbene glycoside from Polygonum multiflorum . Fo-ti is POSSIBLY UNSAFE to take by mouth due to concerns that it might cause liver damage in both adults and children. He, J. Jiang, and Z. Y. Xiong, “Clinical Analysis of drug-induced liver injury caused by, G. Q. Liu, “Clinical analysis of 9 cases of drug-induced liver injury by, X. H. Zhou and X. Qiu, “Clinical analysis of 11 cases of drug-induced liver injury by, H. Dong, D. Slain, J. Cheng, W. Ma, and W. Liang, “Eighteen cases of liver injury following ingestion of, J. Xu, M. R. Wang, C. L. He, Y. H. Sui, and F. Qiao, “Liver injury by peroral, S. G. Zhang, W. Yi, R. J. Hao, J. F. Peng, and G. Zhao, “Analysis of 13 cases of liver damage caused by, K. A. Jung, H. J. Min, S. S. Yoo et al., “Drug-induced liver injury: twenty five cases of acute hepatitis following ingestion of, E. Ding, “Clinical analysis on the treatment of drug-induced liver injury by, X. J. Xie, K. F. Ma, and Y. Liu, “Analysis of liver injury induced by, X. Q. Guo, “Clinical characteristics analysis of liver damage caused by, L. Y. After screening, articles were read in full and extracted by two independent reviewers (Xiang Lei and Jing Chen). SWP: Shou-Wu-Pian; SWW: Shou-Wu-Wan; OAP: oral administration of powder; SIW: soaked in water to drink; P. HSW: processed HSW; R. HSW: raw HSW; HSW: unclear whether it was processed; RD: recommended dosages; NA: not available. It has also been shown to protect liver cells from damage by … Symptoms of liver damage occur mostly a month or so after taking the medicine, mainly including jaundice, fatigue, anorexia, and yellow or tawny urine. People should be alert to liver damage when taking HSW preparations. Patient details recorded from published case reports. Although only 25 cases of case reports have the HSW dosage information, 14 cases exceed maximum dosages (12 g/d). Traditional herbalism uses the roots of … Case reports and case series are included in the review if they reported factual data on liver damage related to HSW. 2020 Aug 6;12(8):2353. doi: 10.3390/nu12082353. Sign up here as a reviewer to help fast-track new submissions. 2017 May 5;203:182-190. doi: 10.1016/j.jep.2017.03.046. If fatigue, anorexia, nausea, yellowing of skin and sclera, yellow urine, and other symptoms appear after medication, patients should be alerted to the occurrence of liver damage and promptly stop the medicine and treatment. The kidneys are often referred to as “the root of vitality” in TCM, since they are involved in essential life processes, including supporting our metabolism, reproduction, blood clean… Polygonum multiflorum (witch hazel) is often recommended for topical use but in traditional Chinese medicine it is also used orally. Objective. Reports of hepatitis associated with Polygonum multiflorum have also been reported in the published literature (1–4).  |  Although many studies suggest that processing could reduce the toxicity of HSW [15, 35], all HSW products may lead to liver damage regardless of herbal processing. Reynoutria multiflora (synonyms Fallopia multiflora and Polygonum multiflorum) is a species of flowering plant in the buckwheat family Polygonaceae. High cholesterol 4. : A Systematic Review of Case Reports and Case Series", Evidence-Based Complementary and Alternative Medicine, vol. 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